I have been away from the Picoblaze for a while (Spartan 6 was the last project) and am now attempting to bring up a Picoblaze design on a Spartan-7 board (Digilent CMOD S7). I'm running Vivado 2018.3 and have the ISE LabTools installed under Windows 10 64-bit. The Picoblaze seems to be behaving as expected in design and the assembler seems to work as well. I'm having problems getting the jtag_loader working for this design. Has anyone been able to use the jtag loader for a Spartan-7 design under Windows 10?