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Edico Genome and Children’s Hospital of Philadelphia set Guiness World Record: 1000 pediatric genomes processed in 2 hrs, 25 min

Xilinx Employee
Xilinx Employee
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Last week, Edico Genome and Children’s Hospital of Philadelphia (CHOP) set a new worlds record in genome processing by analyzing 1000 pediatric genomes through Edico Genome’s DRAGEN Genome Pipeline in two hours and 25 minutes. They accomplished this feat by harnessing 1000 Amazon AWS EC2 F1 instances—cloud acceleration instances that are based on Xilinx UltraScale+ VU9P FPGAs. The team analyzed a pediatric cohort of 1,000 whole genomes supplied by the Center for Applied Genomics (CAG), one of CHOP’s specialized Center of Emphasis.


CAG’s primary goal is translating basic research findings to medical innovations and it’s dedicated to the development of new and better ways to diagnose and treat children affected by rare and complex medical disorders. Results from the rapid analysis will be utilized by the CAG with the hope of uncovering genetic links to common childhood diseases, including asthma, autism, diabetes, epilepsy, obesity, schizophrenia, pediatric cancer and a range of rare diseases. 


“Today’s speed test is a culmination of two years of collaboration between CAG and Edico Genome, including beta-testing their product in our center. We utilize DRAGEN as part of our genomic workflow to achieve our mission of translating basic research findings to medical innovations.  The speed of this technology in processing vast amounts of raw data in a matter of minutes will allow us to deliver actionable results in hours—an important capability as we go forward in realizing the benefits of precision medicine for children and families,” said Hakon Hakonarson, M.D., Ph.D., director of CAG at CHOP.


For more information about Edico Genome’s DRAGEN Genome Pipeline, see: